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Description

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Endogenous and exogenous reactive oxygen species, such as superoxide anion, hydroxyl radical, hypohalite radical, and hydrogen peroxide, and reactive nitrogen species, such as nitric oxide, peroxynitrite, and nitrite, play a major role in the airway inflammation and are determinants of asthma severity

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Endogenously, free radicals are generated as natural by-products of metabolic processes, such as mitochondrial electron transport, enzymatic reactions, and immune responses [2]

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doi: 10.1053/jhep.2003.50351

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